Root 66 Cannabis Dispensary

Root 66 Cannabis Dispensary in St Charles

3004 S St Peters Pkwy
St Charles, MO 63303

Hours of Operation:


Payment Methods:

Cash & Debit Only

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Root 66 Cannabis Dispensary in St Charles located at 3004 S St Peters Pkwy is now open to help MO marijuana card holders get access and shop for medical marijuana products.

Root 66 menu products are available for MMJ Patients near St Charles diagnosed with a Qualifying Condition from a Certified MMJ Doctor.

Root 66 Cannabis St Charles Dispensary Menu

Any interactions with the live menu below, such as, but not limited to, product searches or order placing, take place directly with the menu provider. has no access to any personal data or transactional information when you are interacting with the menu.

What People Are Saying

Ashley Griffith
Ashley G.
18:25 12 Jul 21
I have been going to Root66 since a week or so after it opened and absolutely love the environment and energy every time I am there. They have a nice variety of flower every time with super nice employees to help along the way. This is my go to dispensary!read more
Kayla Nettles
Kayla N.
01:29 16 Jun 21
First time ever walking into a dispensary and had no idea what to expect. Very friendly staff, knew all the ins and outs of their products and answered all of my questions to get me the right products. Great selection to suit anyone. Will definitely be going back!read more
Reginald Hightower
Reginald H.
02:51 08 Jun 21
Excellent store. Store was very clean and had a very friendly staff. Best dispensary I’ve been to in Missouri. Will definitely be backread more
Reginald Hightower
Reginald H.
16:21 30 May 21
Excellent store. Store was very clean and had a very friendly staff. Prices are a bit steep, but overall great selection. Will definitely be backread more
Dj Adelsberger
Dj A.
01:27 26 May 21
First timer to a dispensary In Missouri so I was definitely skeptical about going. The place was really nice and the staff was friendly too. I dealt with Nick, he talk to me through the different types of flowers they have and what cart was best. I definitely recommend this place and I will be back for more
My Cousin Vinny
My Cousin V.
22:34 15 May 21
The White Widow I got from here is gas. I really can’t wait until the pricing of everything gets better though. Very nice aesthetic in the store. Employees are nice and more
Robert Smith
Robert S.
17:50 13 May 21
Best shop here in st Charles Co,Premium Flower there,great experience, will shop again
Heather Hex
Heather H.
15:01 12 May 21
Went there opening day on 4/20 and was very pleased they had a decent selection of flower and price range on flower. I'm in love with their Keef beverages, very delicious! The store was very clean and the staff was very helpful!read more
Nick Evans
Nick E.
19:47 11 May 21
Place was nice and clean and the staff was friendly. I would suggest anybody planning on purchasing from here to check out the product when they hand it to you at the register if possible because what was shown in the glass case and what I opened up when I got home was two completely different products I was expecting 3.5g of Blue dream buds and what I got instead was 3.5g of Blue Dream shake/trim. I'm extremely disappointed and what I received I have reached out and emailed the company also and have not received a response.UPDATE: I reached out to Root 66 and spoke with one of the managers and explained my situation and they are going to make it right by replacing the 3.5g with a similar product. I will update my rating from 2 stars to 5 stars for the customer service they showed me more
Christine Todd
Christine T.
21:19 21 Apr 21
Went on opening day. The facility is great. The staff was knowledgeable and very helpful. I very much enjoyed the experience and look forward to the expanding products and to visiting again. Basically 10/ more
Jack Schwab
Jack S.
16:04 20 Apr 21
Very nice and helpful staff. A bit limited on selection but I imagine it will change with time and if recreational is passed. All in all very good more
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